TO INTERPRET AND ANALYZE THE CHANGING PATTERNS OF HISTOLOGY AND DIRECT IMMUNOFLUORESCENCE FINDINGS IN MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS

To interpret and analyze the changing patterns of histology and direct immunofluorescence findings in membranoproliferative glomerulonephritis

Background: Speedometer Membranoproliferative glomerulonephritis has in the recent past been regrouped into immune complex-mediated (ICM MPGN) disease (driven by the classical complement pathway) and complement-mediated (C3GN) disease (driven by the alternative complement pathway) based on pathogenetic role of alternative complement pathway and imm

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Screening of drug candidates against Endothelin-1 to treat hypertension using computational based approaches: Molecular docking and dynamics simulation.

Hypertension (HTN) is a major risk factor for cardiovascular and renal diseases, cerebrovascular accidents (CVA) and a prime underlying cause of worldwide morbidity and mortality.Hypertension is a complex condition and a strong interplay of multiple genetic, epigenetic and environmental factors is involved in its etiology.Previous studies showed an

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Seismic signature detection during the 2018 Anak Krakatau flank collapse and tsunami using seismic amplitudes from regional-scale monitoring

Abstract On 22 December 2018, the major flank collapse of Anak Krakatau volcano generated a tsunami that struck the surrounding coasts of Java and Sumatra islands in Indonesia without warning.It was later suggested that the corresponding seismic event lacked the body-wave arrivals typical of tectonic earthquakes, causing difficulties for the automa

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